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pentobarbital will decrease the level or impact of lumacaftor/ivacaftor by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.pentobarbital will decrease the extent or outcome of darunavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will decrease the level or influence of vinorelbi

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